; check for availability of ldl after reaching box t1
(defrule check-ldl-at-t1 "Check for ldl"
  ?f1 <- (patient2 (ldl ?ldl)
		   (done ?done)
		   (state ?state)
		   (name ?name))
  (test (= ?ldl -1))  ; see other rules with ldl > 0
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state t1)))
  =>
  (printout t crlf 
	    "Please input patient " ?name "'s ldl value [-1 if no value]"crlf)
  (bind ?answer (read))
  (if (and (numberp ?answer) (> ?answer 0)) then
	  (modify ?f1 (ldl ?answer)) ; do not modify state here
   else
        (printout t crlf
		 "-------------------------------------------------------"crlf)
	(printout t "Please obtain ldl test on" ?name crlf)
	(printout t
		 "-------------------------------------------------------"crlf)
	(modify ?f1 (done yes))))

; rule to check the age of the ldl value
; for treated patient must be after treatment
(defrule check-treat-ldl-date "after treatment begins"
  ?f1 <- (patient2 (name ?name) (ldl-date ?ldl-date) 
		   (treatment-date ?treatment-date)
		   (done ?done) (state ?state))
  (test (<  ?ldl-date ?treatment-date)) 
  (test (= 0 (str-compare ?done no)))
=>
  (printout t "-------------------------------------------------------"crlf)
  (printout t "| Last ldl value for " ?name 
	    " is before the latest treatment." crlf)
  (printout t "| Please obtain a value on treatment." crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1 (done yes)))


; Rule for box t4 chd low risk
(defrule ruleT4 "no chd low risk"
  ?f1 <- (patient2 (name ?name) (done ?done) (risk ?risk)
		   (state ?state) (chd ?chd))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?chd no)))
  (test (= 0 (str-compare ?state t1))) ; state
  (test (< ?risk 2))
  =>
  (modify ?f1 (state t4)))

; Rule for box t5 chd high risk
(defrule ruleT5 "no chd high risk"
  ?f1 <- (patient2 (name ?name) (done ?done) (risk ?risk)
		   (state ?state) (chd ?chd))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?chd no)))
  (test (= 0 (str-compare ?state t1))) ; state
  (test (>= ?risk 2))
  =>
  (modify ?f1 (state t5)))


; Rule for box t6 chd high risk
(defrule ruleT6 "no chd high risk"
  ?f1 <- (patient2 (name ?name) (done ?done)
		   (state ?state) (chd ?chd))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?chd yes)))
  (test (= 0 (str-compare ?state t1))) ; state
  =>
  (modify ?f1 (state t6)))



; Rule for box t4 responding
(defrule ruleT4good "responding"
  ?f1 <- (patient2 (name ?name) (done ?done) (ldl ?ldl)
		   (state ?state) (treatment ?treatment))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state t4))) ; state
  (test (< ?ldl 160))
  =>
  (printout t crlf)
  (printout t "Patient " ?name " is responding well to "
	    ?treatment " therapy"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (printout t "| The LDL of "?ldl" is below the goal of 160 mg/dl"crlf)
  (printout t "| Continue the current therapy                        |"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1 (done yes) (state tgood)))

; Rule for box t4 not responding
(defrule ruleT4bad "not responding"
  ?f1 <- (patient2 (name ?name) (done ?done) (ldl ?ldl)
		   (state ?state) (treatment ?treatment))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state t4))) ; state
  (test (> ?ldl 160))
  =>
  (printout t crlf)
  (printout t "Patient " ?name " is not responding well to " 
	    ?treatment " therapy" crlf)
  (printout t "-------------------------------------------------------"crlf)
  (printout t "| The LDL of "?ldl" is above the goal of 160 mg/dl"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1  (state tbad)))


; Rule for box t5 responding
(defrule ruleT5good "responding"
  ?f1 <- (patient2 (name ?name) (done ?done) (ldl ?ldl)
		   (state ?state) (treatment ?treatment))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state t5))) ; state
  (test (< ?ldl 130))
  =>
  (printout t crlf)
  (printout t "Patient " ?name " is responding well to " 
	    ?treatment " therapy" crlf)
  (printout t "-------------------------------------------------------"crlf)
  (printout t "| The LDL of "?ldl" is below the goal of 130 mg/dl"crlf)
  (printout t "| Continue the current therapy                        |"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1 (done yes) (state tgood)))

; Rule for box t5 not responding
(defrule ruleT5bad "not responding"
  ?f1 <- (patient2 (name ?name) (done ?done) (ldl ?ldl)
		   (state ?state) (treatment ?treatment))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state t5))) ; state
  (test (> ?ldl 130))
  =>
  (printout t crlf)
  (printout t "Patient " ?name " is not responding well to "
	    ?treatment " therapy"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (printout t "| The LDL of "?ldl" is above the goal of 130 mg/dl"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1  (state tbad)))


; Rule for box t6 responding
(defrule ruleT6good "responding"
  ?f1 <- (patient2 (name ?name) (done ?done) (ldl ?ldl)
		   (state ?state) (treatment ?treatment))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state t6))) ; state
  (test (< ?ldl 100))
  =>
  (printout t crlf)
  (printout t "Patient " ?name " is responding well to "
	    ?treatment " therapy"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (printout t "| The LDL of "?ldl" is below the goal of 100 mg/dl"crlf)
  (printout t "| Continue the current therapy                        |"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1 (done yes) (state tgood)))

; Rule for box t6 not responding
(defrule ruleT6bad "not responding"
  ?f1 <- (patient2 (name ?name) (done ?done) (ldl ?ldl)
		   (state ?state) (treatment ?treatment))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state t6))) ; state
  (test (> ?ldl 100))
  =>
  (printout t crlf)
  (printout t "Patient " ?name " is not responding well to "
	    ?treatment " therapy"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (printout t "| The LDL of "?ldl" is above the goal of 100 mg/dl"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1  (state tbad)))


; Rule for early non responders
(defrule ruleTbadearly "not responding"
  ?f1 <- (patient2 (name ?name) (done ?done) (treatment-date ?treatment-date)
		   (state ?state))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state tbad))) ; state
  (test (not (six-months ?treatment-date)))
  =>
  (printout t "| Patient has been on treatment for less than 6 months|"crlf)
  (printout t "| Continue treatment for 6 months before evaluating   |"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1  (done yes)(state tz)))

; Rule for late nonresponders to diet
(defrule ruleTbaddiet1 "no chd low risk"
  ?f1 <- (patient2 (name ?name) (done ?done) (ldl ?ldl) (chd ?chd)
		   (treatment ?treatment) (treatment-date ?treatment-date)
		   (risk ?risk) (state ?state))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state tbad))) ; state
  (test (= 0 (str-compare ?chd no)))
  (test (= 0 (str-compare ?treatment diet)))
  (test (six-months ?treatment-date))
  (test (< ?risk 2))
  (test (< ?ldl 190))
  =>
  (printout t "| Although patient has not responded to diet,         |"crlf)
  (printout t "| the LDL is not high enough to justify drug therapy. |"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1  (done yes)(state tz)))

; Rule for late nonresponders to diet
(defrule ruleTbaddiet2 "no chd high risk"
  ?f1 <- (patient2 (name ?name) (done ?done) (ldl ?ldl) (chd ?chd)
		   (treatment ?treatment) (treatment-date ?treatment-date)
		   (risk ?risk) (state ?state))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state tbad))) ; state
  (test (= 0 (str-compare ?chd no)))
  (test (= 0 (str-compare ?treatment diet)))
  (test (six-months ?treatment-date))
  (test (>= ?risk 2))
  (test (< ?ldl 160))
  =>
  (printout t "| Although patient has not responded to diet,         |"crlf)
  (printout t "| the LDL is not high enough to justify drug therapy. |"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1  (done yes)(state tz)))

; Rule for late nonresponders to diet
(defrule ruleTbaddiet3 "with chd"
  ?f1 <- (patient2 (name ?name) (done ?done) (ldl ?ldl) (chd ?chd)
		   (treatment ?treatment) (treatment-date ?treatment-date)
		   (state ?state))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state tbad))) ; state
  (test (= 0 (str-compare ?chd yes)))
  (test (= 0 (str-compare ?treatment diet)))
  (test (six-months ?treatment-date))
  (test (< ?ldl 130))
  =>
  (printout t "| Although patient has not responded to diet,         |"crlf)
  (printout t "| the LDL is not high enough to justify drug therapy. |"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1  (done yes)(state tz)))

; Rule for late nonresponders to diet who are drug candidates
(defrule ruleTbaddiet4 "candidates for drug therapy"
  ?f1 <- (patient2 (name ?name) (done ?done) 
		   (treatment ?treatment) (treatment-date ?treatment-date)
		   (state ?state))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state tbad))) ; state
  (test (= 0 (str-compare ?treatment diet)))
  (test (six-months ?treatment-date))
  =>
  (printout t "| Consider advancing to drug therapy.                 |"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1  (done yes)(state tz)))


; Rule for late nonresponders to drug therapy
(defrule ruleTbaddrug "candidates for drug therapy"
  ?f1 <- (patient2 (name ?name) (done ?done) 
		   (treatment ?treatment) (treatment-date ?treatment-date)
		   (state ?state))
  (test (= 0 (str-compare ?done no)))
  (test (= 0 (str-compare ?state tbad))) ; state
  (test (= 0 (str-compare ?treatment drug)))
  (test (six-months ?treatment-date))
  =>
  (printout t "| Consider advancing therapy.                         |"crlf)
  (printout t "-------------------------------------------------------"crlf)
  (modify ?f1  (done yes)(state tz)))