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<td colspan="2" bgcolor="FFE3F3"> 更新時間：2008-6-18 16:05:05 【字體：<a href="javascript:fontZoomA();" class="top_UserLogin">小</a> <a href="javascript:fontZoomB();" class="top_UserLogin">大</a>】</td>
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<div> 《柳葉刀》雜志(Lancet2003;362:869-875)上將發表的一項報告說，糖蛋白粘附因子L1在卵巢和子宮腫瘤內的表達明顯與其預后不良有關。 德國癌癥研究中心的阿爾特沃格(PeterAltevogt)和同事評估了58名卵巢癌病人和72名子宮癌病人腫瘤標本里L1的表達情況，還檢測了是否能在病人血漿里檢測到可溶性L1。<br />
在兩組病人中，L1的表達都與分化不良的腫瘤和晚期腫瘤有關，而且這種表達還是預后差的有力預測因子(p<0.00001)。甚至組織學類型屬于通常后果較好的那種，L1的表達也與疾病進展有關。III/IV期病人的血漿標本里還發現可溶性L1，可能是用于檢測或隨訪病人的一種有用標志物，盡管這還需要更多研究。</div>
<div> “為L1為主的診斷和預后可能對子宮和卵巢癌的更好管理和治療有重要作用”. </div>
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